Detalhe da pesquisa
1.
Mechanisms of Resistance to Noncovalent Bruton's Tyrosine Kinase Inhibitors.
N Engl J Med
; 386(8): 735-743, 2022 02 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35196427
2.
Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor.
Blood
; 142(1): 62-72, 2023 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36796019
3.
Characterization of a Long-Acting Site-Specific PEGylated Murine GM-CSF Analog and Analysis of Its Hematopoietic Properties in Normal and Cyclophosphamide-Treated Neutropenic Rats.
Protein J
; 39(2): 160-173, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32172395
4.
A long-acting, mono-PEGylated human growth hormone analog is a potent stimulator of weight gain and bone growth in hypophysectomized rats.
Endocrinology
; 148(4): 1590-7, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17234711
5.
Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity.
Exp Hematol
; 34(6): 697-704, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16728273
6.
PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice.
J Interferon Cytokine Res
; 34(10): 759-68, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24841172
7.
Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b.
J Interferon Cytokine Res
; 33(12): 769-77, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23962003
8.
Recombinant murine growth hormone from E. coli inclusion bodies: expression, high-pressure solubilization and refolding, and characterization of activity and structure.
Biotechnol Prog
; 26(3): 743-9, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20196161
9.
Application of high hydrostatic pressure to dissociate aggregates and refold proteins.
Curr Pharm Biotechnol
; 10(4): 447-55, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19519422
10.
Enhanced circulating half-life and antitumor activity of a site-specific pegylated interferon-alpha protein therapeutic.
Bioconjug Chem
; 19(1): 299-305, 2008 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18020402
11.
A long-acting, highly potent interferon alpha-2 conjugate created using site-specific PEGylation.
Bioconjug Chem
; 16(1): 200-7, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-15656592
12.
Site-specific PEGylation of engineered cysteine analogues of recombinant human granulocyte-macrophage colony-stimulating factor.
Bioconjug Chem
; 16(5): 1291-8, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16173810
13.
Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor.
Bioprocess Int
; 3(4): 52-60, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899681